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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea46229db1e097731b3ace204c6ab802454b2f78c0ef89cd1f4e45c3042444e9' 
  AND token = 'hE2vWtwZ3kJ98mkD+lYQt94HC30Re3mowRhm3kdLvjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}