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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44fe9d6b6d3861c83c132f1d27259366ffaf889e6677aae27c7bfcd90428bd25' 
  AND token = 'VjNTFtxcuBpe6V4jJ6TwM+ybKB2ffCKmN1xLUJBR9Sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}