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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1259129284c4e23d973c8d31a8775903e5b76cec690616786ca7fb20c9dee04c' 
  AND token = 'EeEDKmB+vl77Omv3KJr8DkdvuYeYULoi+9u+jqPvmvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}