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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e38182e4e530e836521706da6f46c1770d3ede438fe1aebb8b1ec829480e8757' 
  AND token = '4rCeq1kX4T9Z7zmAv+lANeT1ysigJ0XYL8C9M8dUOMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}