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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cd217a6e77de21df16bc29bf2ff78427656ff583e78053e64506570ed6112cd' 
  AND token = '5yYWEE23F6TxEa4OAdbRaaZSGIL63ebnPE+LIyaBalA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}