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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c5f8545e4caa090543d2d62cae543d80d2b6eaebf36b9a2041e3e5810415f03' 
  AND token = '/pXMuKfv+Wpj8RTClQOnW+csrEbwbY9rrSAIXEG8FTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}