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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c1ff09835240e935b09b2e24910352810bc428c9341aaaedf9e08cdec0013da' 
  AND token = 'StXNR6FYXhrC0rjjdtBloWBSjzVjtm+J1ZyYiTnI6jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}