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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc9ab5ffccce8ca4f881975000aae0cb4a5544c5526ad9a82b0c51dd817125b8' 
  AND token = 'uRgGGAFMrXuWdXt+UB6FrjHIH3yKACNz3H9kCaN+MaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}