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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0136def9c89720b8ee35a0130f39471beaa1606add38af07620cd2367324fcaa' 
  AND token = 'aXFz67mx70Dc4FMbGlW3w6TzgieIx22zf7A1514mthg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}