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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d8df50a76cf3e1c7e113a257026109ce58a1000d7bf80f77a428748a067c122' 
  AND token = 'DW/N33qO94b+IDEsg9ElShyvrQGDgXfOwyxHbH9R42I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}