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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adc475672425f75ffd8aba518767d1421dec5ea5cc00b2c1e411ec797e379a53' 
  AND token = 'opMrrdvQo9yJztB0M+2ywWeDL3mbU5C5N9aYPjpBd38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}