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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9efb3e7e89f58ad1caa611f7497f5cd4d804802e5c5698fe1533a1cb36faa301' 
  AND token = 'nZXX1VxGFIEdzdX3j3dQiMfXLEqqRckZZ9YrQfugxQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}