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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e3e4ff897fb5ea0740c42c5e34b199ad957e2a7278eba988fd770ff6a53d98c' 
  AND token = '78P11PSdQeMu4yknm/F6lI69shtbpGi60JuRmnmIbR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}