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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7bd278f610aa288637fce2a823e8c9a1ad7fb719106e6427ebe834ef2c04762' 
  AND token = 'ESV/KZYA1eiOm1Fdld/kKKNpR9t1vvyKLstIJBChXc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}