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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b3e8057e81d400ac67d7c781507da99840826f65e16d440893f2d19848dd297' 
  AND token = 'JQAC1miVQbO+32Y6CHOjix5Cd6tQJMNHDzrJugdMQDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}