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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca998d9a06fed9ce7783fa35037586fdccc5c3fec6be37bd866ece9d87c54222' 
  AND token = 'k9m0bgWHk8lJ63u6nz5ARAN9kbp55kuJodRuU5sKiYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}