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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a4f53283a7f6b04a5f9c7f7fb3c0aef280e0398cd9da3aba668031c15133041' 
  AND token = 'rWp5Dx82ZT8Cj9snAr3PdagZOBsk3P1QWILR0bos3KU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}