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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b5e7c41aa09017031f49cfb2999a76e2f4ed4ca12226d1aeb517c2c2fd2821b' 
  AND token = '/McGGnwp2afBMUvK6gcwnSIkxB8trQgzPLgiNG3hpW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}