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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29bd59b2c2b89a249e1fd76e716a6a934e274c7d1fda77ca47b45953d39651e0' 
  AND token = 'jmTA/yXeKKr92H5FbcD3baMhItdBu+IRUw2b9GAGQ9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}