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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6de35e46a00074e89a5b00b491b582fc2543927ee8194e67250427ddb72c4d38' 
  AND token = '8wc1Atn9D9PFWDve+KCFWHZR1Nqa6xIJuGwOVmc1SZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}