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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a233abf66735c998a9f03b87371fd9d8e6213fca33c52d2e695934f07aa8f65' 
  AND token = 'Fp9rK+0tnH2tdA/wvfAiIcgJdZ5870S4uPVPo1YAVvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}