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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '120611747aeedab3278494d8fa0410761b4b7ed93bebbf82b7e527d588c32ff8' 
  AND token = 'EG+xEMQgwu6TNfy53ecvI5/7kaTaQIz5EYuP6Om7IPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}