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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f680d4ef61a9fef54a8c0b3ea899f69cefe7bf8acecb10a8ec7d1fcba4b8723a' 
  AND token = 'eTo4r8tGBy1CExRrYriCeDLOuQ1pmjG9ZsYLjEVTnHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}