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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f125b8796337fa2d0fccb5aacea44042a623bd086c268d6d8be28e3b4eb4745' 
  AND token = '0RYISB7J7bVML1XJLRezSyEqz1VzcoDN0PuhZt4FD5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}