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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d6ede1c1473f0a20628423a04654b530e9f33a8ee715bf9044d71d7c7a13c40' 
  AND token = 'W+FBpzCWWNc6xzHp7ENzB/WucMSz8QRVwr2wLNpA9gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}