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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d06022228fa9ede461d67a3d98cceb6a4bc2448cbe6f6e41cfb5b50b201f0d0' 
  AND token = 'ZDu2e9Tzk0JGHC6eDoIDjPMNvE/8UNSLURc3kiMwnIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}