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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1286ce5373dcb2994efabd0fc08bf7cd7287b80bfc2275ab9c2090f06217bc46' 
  AND token = 'loC5xtfF7Mhuf3MGm8aC5hyduKBEaKJqmlCZdLUdG2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}