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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6654e49332b569dcbf6a2c24485db284977467638bf892a747b66e2470caecc4' 
  AND token = 'kfwDspUZkBvRhvCZK9wayhsJ7TdsUueJzmanB4KGXco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}