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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efed041ea95616df2102e40921e4be62f67b65785f1e9f9041b4bde477e38037' 
  AND token = '/88TobkMRT/eSmYyIR5CXqgmWXWiXEq29X8ANyQkEic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}