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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1deaeac99d2dfd003d47ca0e752324932aa0e3d53cabe5e9d40b641a01bfd85e' 
  AND token = 'i7L9OSe9L4sNnPTLpZB+dcXhgeOVCNbU1WBhdVqNPis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}