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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f2dd276d05ee80e5e6b5d141b375f8a2f80e249212a45de6475a8f1b49d8176' 
  AND token = 'zabOS0JKKiDUM6kNpZaQE7IYxRWPHuZGfNOLnL+aJ5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}