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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc43fb762328ea653d3f9315fac885a779c183098b8c9df1f23f81d95e090edb' 
  AND token = 'Vme4DNUhAijRH889VV4R7HYrPo0nRcyDC2tfp7VuQq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}