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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d59cfde50ba5a7f1419c8efa2dc0c879d2467793ba20ad90d59b4000e2abe53' 
  AND token = 'OLMLim+cLW89F6SdeBTLIuq6d367TwxpmN7tWTfRR6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}