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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '212d1b0b6d1bf55fc59d304906bcc86a4e5cf073d23e07ec5a27a1893bbe06b7' 
  AND token = 'k2dpGrO2tovpPlj8qjPVpUOV78+CLP/Rk2rn6HSJlmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}