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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a45b9ee775fa86e7012bad84d38e2b0ef6b870dfb6f35c233f578b75bd9874dc' 
  AND token = 's/CYvTo8XCRaVi+a1vydvW6MFrhkaa0xcrQjy2tlNY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}