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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41b1093d0eb3ae6f8ba94fba346e58b8b906e738fe97a6a812fe42ee2e43227c' 
  AND token = 'ccjKRlOCDatOd3nFJ0WwvCmtPxHh6sOmPxuJKWW+99s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}