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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edc92aadd01b245bbf80c34b089c2dbf8e6c409f1e387c2649b51923e8612044' 
  AND token = 'RW6UwoEcvXs+oRkGsjIQUc3F1EVydho+4Yr91IHeM4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}