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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22074798e38347ee5399c862d7e50fe117f9749e4b3b6e286c4074af84cf3c50' 
  AND token = 'cPv4FtmpWNmfTjEzqHOUwHYA2q0Itt/Gs6UxQI2ngw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}