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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fd17449ef5f520ef0d1c8c1ff1bd5fad6f1b64a68657ea1354978174e72110f' 
  AND token = 'K/rnQR8/YM9VNSceuLgYt39p6MkXi6zT6ypxDRPpUzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}