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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce6bf34b327a751975d8a16011b6bc8b00c0e748ce837350ecbe1ba10d3bb743' 
  AND token = 'zuNKXN77CETnQwi+4/p45oKZhxlUk5KHF7fqUB4vVsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}