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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d926eea095bf9ca0217c1eb3fc11854ff2eb1930e92b01053c6d2d29624e3b9' 
  AND token = '+JaErD5zSYUE9C45/PybcUJI2dlW/xYD8BmP85sr4zA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}