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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '961c4bdbdf2c29d34231048275b4c1ea0cfb8ae3e0e86ba5af0d62af598b459b' 
  AND token = 'HUgN/mJoJr+6mVdBiBDcUiQzuiose4MVGBh7bwTMi9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}