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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6d21729322a9c1ebf7a018964e56b07f6021c3fe50e4ee0934a94b83b014bd8' 
  AND token = 'XK/bkEMndrolvzy+lJognJC/RVa0j6P6hEMuxhygGe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}