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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b404b57c6de3823c0b5d09bb172b928f5f72354cc6113580bc393c3f138baa8' 
  AND token = 'iWZcJLD5W4Qrde8eX6ZMv6g4cQGYF8hMcXK8V60i/r4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}