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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '258353cc113b1f124c5bc91932cdfccdd2b5ca10935f82b5a03bec3c316bd2e1' 
  AND token = 'fMyXP6UnAUK+VzSV+yCoOVz4v7aOkTgttwEJB0+Kys0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}