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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cd52d39563d619201c8afc9882ac68e0c54625c6d4836ff1613b36c13099818' 
  AND token = '+yPwoJ/L3AzA/Ar+2AzD1obuE7yRtyX0DJnOBSdWgFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}