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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f18e2321676e39cf2f544c172dd5abb0a386013b99099c7a2d690ed7015c75ad' 
  AND token = 'MbYP6sGdk2zMXrkLNcZzk/pt8cqiT21nWy+BNOM6zko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}