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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c990bc1cd9c6598710a1a64caa2b12f40b611e9487b91ef51ecc6fe49b78daa' 
  AND token = 'aH73p+/n/Gka0q/WgpxbUZoQfdpt1kxWGYK+BMCAM0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}