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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20ae7b895958c876cb9687e94cac0ed055b0e2a1a3ab91159b3ac9d5a972f831' 
  AND token = 'Hn3Wtadm75y2EAnjfqwfKhKuYrHm3/xIYh+PEVp5mA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}