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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '549b35b78b54bd5209e83fec222c7c7268a9ea2909011aa95e0a4e34b3c85587' 
  AND token = 'TpyEgm0uUwaNd4cv4WoaUwrx/rd7tV1UVK6VRttaKqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}